Getting from Amsterdam to Prague – Your options between the two cities

by , which can be quite confusing the first time you use it. You can also buy these tickets from the Eurolines office on Damrak near Centraal Station, although that’s not where the buses depart from. From Amsterdam the bus leaves from in front of Amstel Station in Amsterdam, which is about 2 km south of Centraal Station, and easy to reach by tram or metro.